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Table 1 Risk of short-term mortality in suspected, probable, or confirmed EVD cases

From: Determinants of patient survival during the 2014 Ebola Virus Disease outbreak in Bong County, Liberia

Demographic factorsa HRb P value 95 % Conf. Int. AHRc P value 95 % Conf. Int.
 age (years) 1.02 < 0.001 1.01 1.02
 sex 1.51 0.007 1.12 2.03 1.52 0.006 1.13 2.05
Clinical symptoms HR P value 95 % Conf. Int. AHR P value 95 % Conf. Int.
 fever 6.63 0.001 2.12 20.76 2.50 0.116 0.80 7.83
 vomit/nausea 1.93 < 0.001 1.35 2.77 1.58 0.013 1.10 2.26
 diarrhea 1.99 < 0.001 1.42 2.77 1.66 0.003 1.19 2.32
 fatigue 1.58 0.027 1.05 2.38 1.23 0.331 0.81 1.85
 abdominal pain 1.26 0.120 0.94 1.70 1.18 0.273 0.88 1.59
 muscle pain 1.08 0.613 0.79 1.48 0.85 0.307 0.62 1.16
 joint pain 1.38 0.032 1.03 1.86 1.15 0.361 0.85 1.55
 headache 0.95 0.755 0.71 1.28 0.82 0.188 0.61 1.10
 difficulty swallowing 1.17 0.437 0.79 1.74 1.11 0.620 0.74 1.64
 unexplained bleeding 2.17 0.013 1.18 3.99 2.327 0.007 1.26 4.30
 number of symptoms 1.08 0.009 1.02 1.15 1.02 0.549 0.95 1.09
Treatment givend HR P value 95 % Conf. Int. AHR P value 95 % Conf. Int.
 isolation (n = 159) ref ref
 quarantine (n = 70) 0.46 < 0.001 0.31 0.69 0.70 0.081 0.47 1.05
 hospitalization (n = 162) 0.25 < 0.001 0.18 0.35 0.26 < 0.001 0.18 0.37
  1. a216 males and 172 females were used (n = 388) with females as the reference group, for age seventeen records did not include the participant age in the case reporting form (n = 374)
  2. bHazard ratios (HR) determined by Cox regression
  3. cAdjusted hazard ratio (AHR) determined by Cox regression adjusting for age in years
  4. dTreatment given was stratified into three levels of care; with quarantine and hospitalization compared to those who were isolated (reference group)
  5. The risk of short term mortality (within 30 days of EVD symptom onset) in suspected, probable, or confirmed EVD patients was determined by Cox proportional hazard models using demographic factors, clinical symptoms, and highest level of treatment received. The risk of mortality is presented as a hazard ratio (HR) with and without age adjustment (AHR), with P values and 95 % confidence intervals for the hazard ratios. Some demographic data was missing from the case forms, reducing the 391 survival histories to 374 for age and 388 for sex; consequently the AHR only include 374 people