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Table 3 Results from sub group analysis on treatment success

From: Community-based management versus traditional hospitalization in treatment of drug-resistant tuberculosis: a systematic review and meta-analysis

Variables # of Studies Point Estimate 95 % CI
Start year of study     
 2000 or later [6, 11, 14, 30, 3335, 3842] 12 0.64 0.54 0.74
 1999 or earlier [31, 32, 36, 37] 4 0.60 0.44 0.77
Quality of study     
 Very Low [6, 11, 14, 3035, 39, 41] 11 0.65 0.54 0.75
 Low [3638, 40, 42] 5 0.59 0.44 0.74
Adverse Events     
  < 50 % [3436] 3 0.76 0.70 0.82
  > 50 % [6, 3133, 38, 4042] 8 0.63 0.52 0.73
Type of treated patients     
 New cases and previously treated [6, 3032, 3437, 39, 41, 42] 11 0.61 0.52 0.71
 Previously treated patients [11, 33, 38, 40] 4 0.66 0.53 0.78
HIV co-infected patientsa     
 Yes [6, 11, 30, 32, 35, 3740, 42] 10 0.57 0.49 0.64
 No [14, 30, 3335] 6 0.72 0.65 0.79
Patient type     
 MDR [6, 11, 14, 31, 3336, 3942] 12 0.67 0.56 0.78
 MDR and XDR [30, 32, 37] 3 0.51 0.48 0.55
 XDR [38] 1 0.48 0.30 0.66
DOTS-plus Provider     
 Healthcare workers [3032, 36, 38, 4042] 8 0.59 0.48 0.69
 Home care support teams & Family [6, 11] 2 0.78 0.60 0.95
 Home care support teams [14] 1 0.71 0.62 0.80
 Healthcare workers & Family [33, 35] 2 0.72 0.61 0.83
 Family [34] 1 0.79 0.72 0.86
Drug Regimen Model     
 Standardized [6, 11, 30, 3336, 39, 42] 9 0.66 0.53 0.79
 Individualized [31, 32, 37, 38, 40, 41] 6 0.57 0.51 0.62
DOTS-plus Location     
 Health center [14, 30, 33, 34] 4 0.70 0.56 0.84
 Patient home [6] 1 0.84 0.76 0.92
 Patient home and Health center [11, 31, 32, 35] 4 0.61 0.53 0.68
 Hospital [3642] 7 0.57 0.44 0.69
Duration of DOTS-plusa     
 Throughout therapy [6, 11, 14, 30, 3336, 40] 9 0.72 0.65 0.79
 Partial observation [31, 32, 38, 39, 42] 5 0.50 0.43 0.57
Length of treatment (months)a     
  < 18 [32, 42] 2 0.48 0.42 0.55
 18 & above [6, 11, 14, 3035, 37, 3941] 12 0.65 0.56 0.74
Drugs in regimena     
 5 [11, 3032, 34, 35, 3739, 41, 42] 11 0.57 0.49 0.64
  > 5 [6, 33] 2 0.82 0.76 0.89
  1. aNon-overlapping 95 % CI