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Table 2 Sensitivity analyses of women-to-men ratio of relative risks for all-cause mortality associated with marital status

From: Sex differences in the association between marital status and the risk of cardiovascular, cancer, and all-cause mortality: a systematic review and meta-analysis of 7,881,040 individuals

 

Individuals

N

RRR

Lower

Upper

P value

Test for heterogeneity

P value for interaction

I2

χ2

P value

Unmarried vs. married

7,659,086

15

        

Age (years)

         

0.74

<60

775,733

7

0.82

0.70

0.95

0.01

63.10%

16.24

0.01

 

≥60

233,378

4

0.86

0.70

1.06

0.15

33.50%

4.51

0.21

 

Others

6,649,973

4

0.94

0.82

1.07

0.34

0.00%

2.83

0.42

 

Location

         

0.78

Asia

363,787

4

0.87

0.74

1.02

0.09

19.50%

1.7

0.29

 

Europe

6,660,861

7

0.83

0.71

0.97

0.02

49.40%

2.35

0.07

 

America

634,438

4

0.89

0.74

1.08

0.23

47.00%

1.2

0.13

 

Others

Follow-up years

         

0.30

<10

631,422

8

0.86

0.77

0.96

0.01

44.30%

12.57

0.08

 

≥10

7,027,664

7

0.85

0.71

1.02

0.08

47.00%

11.32

0.08

 

Publication years

         

0.60

≤2000

389,351

4

0.84

0.63

1.12

0.22

50.60%

6.07

0.11

 

2001-2009

303,618

8

0.82

0.71

0.95

0.01

39.60%

11.59

0.12

 

≥2010

6,966,117

3

0.93

0.87

0.99

0.02

7.90%

2.17

0.34

 

Widowed vs. married

7,654,572

14

        

Age (years)

         

0.03

<60

915,181

7

0.90

0.80

1.01

0.07

54.20%

13.11

0.04

 

≥60

100,822

3

0.57

0.42

0.77

<0.001

0.00%

0.85

0.65

 

Others

6,638,569

4

1.00

0.99

1.02

<0.001

0.00%

0.72

0.87

 

Location

         

0.64

Asia

265,742

5

0.88

0.76

1.02

0.09

54.20%

5.69

0.22

 

Europe

6,652,570

5

0.81

0.61

1.07

0.14

0.00%

15.24

<0.001

 

America

736,260

4

0.99

0.93

1.06

0.85

0.00%

2.22

0.53

 

Others

NA

         

Follow-up years

         

0.34

<10

611,167

8

0.84

0.73

0.98

0.03

55.30%

15.66

0.03

 

≥10

7,043,405

6

0.94

0.81

1.09

0.43

55.00%

11.12

0.05

 

Publication years

≤2000

375,391

2

0.71

0.36

1.39

0.31

84.10%

6.27

0.01

0.003

2001-2009

313,064

9

0.84

0.76

0.92

<0.001

0.00%

7.71

0.46

 

≥2010

6,966,117

3

1.00

0.99

1.02

0.99

0.00%

0.01

1.00

 

Separated vs. married

7,520,677

12

        

Age (years)

         

0.60

<60

93,931

7

0.81

0.66

0.98

0.03

81.80%

32.99

<0.001

 

≥60

6,649,973

1

0.57

0.18

1.76

0.33

NA

0

NA

 

Others

776,773

4

0.79

0.50

1.24

0.31

69.80%

9.93

0.04

 

Location

         

0.75

Asia

262,237

4

0.62

0.44

0.89

0.01

25.40%

4.02

0.26

 

Europe

6,525,566

5

0.77

0.57

1.04

0.08

88.10%

33.71

<0.001

 

America

732,874

3

0.97

0.83

1.13

0.68

61.70%

5.23

0.07

 

Others

NA

         

Follow-up years

         

0.20

<10

604,276

6

0.73

0.59

0.90

<0.001

76.70%

21.48

<0.001

 

≥10

6,916,401

6

0.93

0.76

1.15

0.50

65.20%

14.36

0.01

 

Publication years

         

0.94

≤2000

375,391

2

1.01

0.65

1.57

0.96

23.00%

1.3

0.26

 

2001-2009

179,169

7

0.72

0.59

0.87

<0.001

34.20%

9.12

0.17

 

≥2010

6,966,117

3

0.89

0.80

1.00

0.05

80.20%

10.12

0.01

 

Never married vs. married

7,511,483

10

        

Age (years)

         

0.20

<60

767,579

5

0.89

0.81

0.97

0.01

22.40%

5.16

0.3

 

≥60

93,931

1

0.54

0.31

0.95

0.03

NA

0

NA

 

Others

6,649,973

4

0.99

0.97

1.02

0.59

0.00%

0.95

0.8

 

Location

         

0.51

Asia

232,631

3

0.87

0.66

1.15

0.31

0.00%

1.62

0.44

 

Europe

6,658,279

5

0.85

0.71

1.01

0.06

71.40%

14.01

0.01

 

America

620,573

2

0.94

0.86

1.03

0.18

0.00%

0.62

0.43

 

Others

NA

         

Follow-up years

         

0.47

<10

447,064

3

0.93

0.83

1.04

0.07

40.20%

3.34

0.19

 

≥10

7,052,854

6

0.84

0.70

1.02

0.21

50.20%

10.04

0.07

 

Others

11,565

1

1.44

0.59

3.50

0.42

NA

0

NA

 

Publication years

         

0.21

≤2000

414,446

3

0.86

0.69

1.08

0.19

58.20%

4.78

0.09

 

2001-2009

130,920

4

0.77

0.61

0.98

0.03

0.00%

2.55

0.59

 

≥2010

6,966,117

3

0.99

0.97

1.01

0.38

0.00%

1.95

0.38

 
  1. Abbreviations: N number of studies; NA not available.