Incidence and mortality trends of neglected tropical diseases and malaria in China and ASEAN countries from 1990 to 2019 and its association with the socio-demographic index

Table 2 Join-point regression results, periods with uptrends of ASIRs and ASMR of NTDM

Location	Start year	End year	APC (95% CI) (%)	P value
ASIR
Global	1998	2007	0.4 (0.3 to 0.5)	< 0.001
	2015	2019	0.4 (0.1 to 0.7)	0.026
China	1995	2000	3.7 (3.2 to 4.1)	< 0.001
	2000	2009	6.3 (6 to 6.6)	< 0.001
	2014	2017	10.4 (6.1 to 14.9)	< 0.001
Brunei	2000	2005	4 (3.5 to 4.6)	< 0.001
	2005	2010	0.8 (0.5 to 1.2)	< 0.001
Cambodia	1994	2001	2.7 (1.7 to 3.7)	< 0.001
Indonesia	2004	2010	8.3 (7.4 to 9.2)	< 0.001
Laos	1990	1993	13.6 (9.6 to 17.7)	< 0.001
	1993	1998	5.5 (3.9 to 7.2)	< 0.001
	2005	2013	3.9 (2.5 to 5.3)	< 0.001
Malaysia	2010	2015	4.3 (3.6 to 5.1)	< 0.001
Myanmar	1994	2006	1.4 (1 to 1.9)	< 0.001
	2006	2010	10.5 (8.1 to 13)	< 0.001
Philippines	2000	2006	5.5 (5.2 to 5.8)	< 0.001
	2006	2009	6.8 (6.1 to 7.4)	< 0.001
	2015	2019	4.2 (3.7 to 4.8)	< 0.001
Singapore	2000	2005	6.9 (4.4 to 9.4)	< 0.001
	2010	2014	7.5 (4.5 to 10.6)	< 0.001
Thailand	2005	2010	2 (1.5 to 2.4)	< 0.001
	2015	2019	2.4 (1.9 to 2.8)	< 0.001
Viet Nam	1990	2000	0.7 (0.6 to 0.8)	< 0.001
	2014	2017	3.2 (1.5 to 4.9)	0.001
ASMR
China	2000	2005	3.7 (2.1 to 5.2)	< 0.001
Brunei	2001	2005	1.8 (0.5 to 3.2)	0.010
	2008	2016	1.3 (1 to 1.7)	< 0.001
Myanmar	1998	2008	10 (7.7 to 12.4)	< 0.001
Singapore	1998	2005	14.6 (6.3 to 23.5)	0.001

APC, annual percentage change; ASIR, age-standardized incidence rate; ASMR, age-standardized mortality rate; NTDM, neglected tropical diseases and malaria

ISSN: 2397-0642